We had a keynote today by Ben Galbraith from Ajaxian about the current state of Ajax. This was a standout talk and my highlight of zendcon08. He is an excellent presenter, not just by having great slides/animations, but by his descriptions which where only technical where required. He also had an excellent structure and pacing to his presentation.
The content was very interesting. In summary he believes a new wave of desktop-like applications on the browser is upon us.